Dr. Leonid A. Gavrilov, Ph.D. Research Associate Center on Aging NORC and The University of Chicago 1155 E 60th Street Chicago, IL 60637 |
Phone: (773) 256-6359 FAX: (773) 256-6313 E-mail address: |
Research interests: Mechanisms of aging,
mortality,
and longevity.
EDUCATION:
1980 - Ph.D. in Genetics, Department
of Biology, Moscow State
University,
Russia
1976 - Master of Science, Department
of Chemistry, Moscow State
University,
Russia
PROFESSIONAL EXPERIENCE:
1997-Present Research Associate, Center on Aging, NORC and The University of Chicago
1991-1997 Principal Research Scientist, A.N.Belozersky Institute, Moscow State University, Russia.
1987-1991 Senior Research Scientist, A.N.Belozersky Institute, Moscow State University, Russia.
1980-1987 Research Scientist,
A.N.Belozersky
Institute, Moscow State University, Russia.
EDITORIAL, REVIEW AND OTHER PROFESSIONAL ACTIVITIES:
Editorial
Board
Member:
Experimental Gerontology, Elsevier Publ.; Journal
of Anti-Aging Medicine, Mary Ann Liebert Inc. Publishers, USA
(1998-2004);
Rejuvenation
Research, Mary Ann Liebert Inc. Publishers, USA; The
ScientificWorldJOURNAL (http://www.thescientificworld.com/);
Health Care in Later Life, Arnold Publishers, UK (1996-1998); Theoretical Biology and Medical Modelling,
Associate Editor, BioMed Central.
Referee for scientific journals: AGE (Journal of the American Aging Association), Annals of Human Genetics, Biogerontology, Biology Letters (Royal Society), BioMed Central, Demography, European Journal of Population, Experimental Gerontology, Genus, International Journal of Epidemiology, Journal of Anti-Aging Medicine, Journal of Gerontology, Journal of the American Geriatrics Society, Journal of Theoretical Biology, Mathematical Population Studies, Population, Population and Development Review, Social Biology, Sociological Methodology, The Scientific World Journal
Book reviewer for journals: New England Journal of Medicine, Population and Development Review, Age and Ageing, Ageing and Society.
Expert (Research
Proposal Reviewer):
Canadian Institutes of Health Research (CIHR, http://www.cihr-irsc.gc.ca/)
Member: Gerontological Society of America (GSA). International Union for the Scientific Study of Population (IUSSP). Population Association of America (PAA), Social Science History Association (SSHA), European Association for Population Studies (EAPS), Russian Genealogical Society, The Science Advisory Board (Senior Member: http://www.scienceboard.net/)
Consultant for the National Institute on Aging: National Institutes of Health Professional Service Contract #263 SDN74858 "Inventory of data resources on familial aggregation of human longevity that can be used in secondary analysis in biodemography of aging", 35pp. Submitted to NIA on 05/29/98.
Consultant (ad
hoc reviewer) for the National Research Council at the National
Academy
of Sciences of the United States.
RESEARCH GRANTS:
National Institute on Aging grant, NIH (grant #1 K02 AG00976-01A2, 04/15/2001 - 03/31/2006), Biodemography of Human Longevity-Training Program. (Principal Investigator).
National Institute on Aging grant, NIH (grant #1R03 AG15698-01, May 1, 1998 - April 30, 1999), Biodemographic Study of Parental Age Effects on Lifespan.(Principal Investigator).
Center on Aging Pilot Project grant "Biodemographic Study of Parental Age Effects on Human Longevity" (PI) provided by the Center on Aging, NORC/University of Chicago, grant P20 AG12857 from the National Institute on Aging.
The European Community grant (INTAS grant #93-1617-ext) 1996-97, The Mechanisms of Human Longevity, an Association of Parental Characteristics and Longevity of Their Children (CO-PI: Representative of the Research Team).
The European Community grant (INTAS grant #93-1617) 1995-96, The Mechanisms of Human Longevity, an Association of Parental Characteristics and Longevity of Their Children (CO-PI: Representative of the Research Team).
International Science Foundation grant (ISF) 1995 Research Grant #M7E300, Parental Age and Offspring Longevity (Human) (PI).
International Science Foundation grant (ISF) 1994 Research Grant #M7E000, Parental Age and Offspring Longevity (Human) (PI).
International Science Foundation grant (ISF) 1994
Research
Grant #SBI000, Measurement and Analysis of Oldest-Old Mortality
(CO-PI).
AWARDS
Cited by “Who’sWho in America” in Marquis Who’sWho, 2002 and 2003 Editions.
Gordon Research Conference on the Biology of Aging. Travel award. (Il Ciocco, Italy, 10-15 May, 1998).
REVES10 International Meeting on Health Expectancy (Tokyo, October 9-12, 1997). Travel award from the Organizing Committee.
Gordon Research Conference on the Biology of Aging. Travel award. (Ventura, CA, 5-10 January, 1997)
U.S. Civilian Research and Development Foundation (CRDF), 1996, Proposal Development Program Award (grant #PDP48).
International Science Foundation (ISF) 1994 Emergency Award for Russian Scientists of the Top Category.
International Science Foundation (ISF) 1993 Emergency Award.
A.N.Belozersky Institute 1991 Award for the best scientific research in the Institute in 1990-1991.
Moscow Society of Naturalists 1989 Award for the best scientific research in natural science in 1986-1988.
European
Population
Conference (Paris, October 1991). Travel award from the Organizing
Committee.
RELEVANT PUBLICATIONS (partial list):
Books:
Gavrilov L.A., Gavrilova N.S. The Biology of Life Span: A Quantitative Approach, NY: Harwood Academic Publisher, 1991, 385p.
This book is selected and cited by Encyclopedia Britannica as recommended reference (see "Additional reading"). The book was also reviewed by Nature (1991, 352: 767), British Medical Journal (1992, 305: 431), BioEssays (1993, 15: 359), Quarterly Review of Biology (1993, 68: 92), Population Studies (1992, 46: 366), Population and Development Review (1992, 18: 555 and 1998, 24: 381), Am.J.Epidemiology (1994, 139: 231), Experimental Gerontology (1992, 27: 251), Gerontologist (1991, 31: 707), Human Biology (1992, 64: 630), J.Epidemiology & Community Health (1992, 46: 630), J.Institute of Actuaries (1992, 119: 379), Age and Ageing (1992, 21: 386), Ageing and Society (1991, 11: 509), Archives of Gerontology and Geriatrics (1992, 15: 192), Educational Gerontology (1993, 19: 92), Free Radical Biology & Medicine (1992, 12: 331).
Gavrilov,
L. A. (1990). Podra Prolongarse la Vida del Hombre? (In
Spanish).
Moscow: Mir, 200p.
Book chapters:
Gavrilova, N.S., Gavrilov, L.A. Human longevity and reproduction: An
evolutionary perspective. In: Voland, E.; Chasiotis, A. &
Schiefenhoevel, W. (eds.). Grandmotherhood
- The Evolutionary
Significance of the Second Half of Female Life. Piscataway, NJ:
Rutgers
University
Press, 2005 (in press).
Gavrilova, N.S., Gavrilov, L.A., Semyonova, V.G., Evdokushkina,
G.N., Ivanova, A.E. Patterns of violent crime in Russia.
In: Pridemore, W.A. (ed.). Ruling
Russia: Law, Crime, and Justice in a Changing Society. Boulder,
CO: Rowman & Littlefield Publ., Inc. (forthcoming in July
2005).
Gavrilov, L.A., Gavrilova, N.S. Early-life factors modulating lifespan. In: Rattan, S.I.S. (Ed.). Modulating Aging and Longevity. Kluwer Academic Publishers, Dordrecht, The Netherlands, 2003, 27-50.
Gavrilov L.A., Heuveline P. Aging of Population. In: Paul Demeny and Geoffrey McNicoll (Eds.) The Encyclopedia of Population. New York, Macmillan Reference USA, 2003, vol.1, 32-37.
Gavrilov, L.A., Gavrilova, N.S. Genetics. In: David J. Ekerdt (ed.) Macmillan Encyclopedia of Aging, New York, Macmillan Reference USA, 2002, vol.2, 536-538.
Gavrilova, N.S., Gavrilov, L.A. Evolution of Aging. In: David J. Ekerdt (ed.) Macmillan Encyclopedia of Aging, New York, Macmillan Reference USA, 2002, vol.2, 458-467.
Gavrilov, L.A., Gavrilova, N.S. Human
longevity and parental age at
conception. In: J.-M.Robine et al. (eds.)
Sex
and Longevity: Sexuality, Gender, Reproduction, Parenthood,
Berlin,
Heidelberg: Springer-Verlag, 2000, 7-31.
Articles:
Gavrilov LA, Gavrilova NS. Why We
Fall Apart. Engineering's Reliability Theory Explains Human Aging. IEEE Spectrum, 2004, 41(9): 30-35.
Gavrilova NS, Gavrilov LA,
Semyonova VG, Evdokushkina GN. Does
exceptional human longevity come with high cost of infertility? Testing
the evolutionary theories of aging. Annals of the New York Academy
of Sciences, 2004, 1019: 513-517.
Gavrilov LA, Gavrilova NS. Early-life
programming of aging and
longevity: The idea of high initial damage load (the HIDL
hypothesis). Annals of the
New York Academy of Sciences, 2004,
1019: 496-501.
Gavrilov LA, Gavrilova NS. The
reliability-engineering approach to the
problem of biological aging. Annals of the New York Academy of
Sciences, 2004, 1019: 509-512.
Gavrilov LA, Gavrilova NS. Early-Life
Exposure, Season of Birth and Gender Differences in Human Life Span.
Science, 2004, 305(5691): 1739
(letter published in Science online
at: http://www.sciencemag.org/cgi/eletters/305/5691/1736#1075).
Gavrilova N.S., Gavrilov L.A., Evdokushkina, G.N., Semyonova, V.G. Early-life predictors of human longevity: Analysis of the 19th Century birth cohorts. Annales de Demographie Historique, 2003, 2: 177-198.
Gavrilov L.A., Gavrilova N.S. The quest for a general theory of aging and longevity. Science's SAGE KE (Science of Aging Knowledge Environment) for 16 July 2003; Vol 2003, No.28, 1-10. http://sageke.sciencemag.org
Gavrilov, L.A., Gavrilova, N.S. Evolutionary theories of aging and longevity. TheScientificWorldJOURNAL, 2002, 2: 339-356. Available: http://www.thescientificworld.com/
Gavrilov L.A. Scientific legitimacy of the term "Anti-Aging." Journal of Anti-Aging Medicine, 2002, 5(2): 239-240.
Gavrilov L.A., Gavrilova N.S., Olshansky S.J., Carnes B.A. Genealogical data and biodemography of human longevity. Social Biology, 2002, 49(3-4): 160-173.
Gavrilov L.A., Gavrilova N.S. The quest for the theory of human longevity. The Actuary, 2002, 36(5): 10-13.
Gavrilov, L.A., Gavrilova, N.S. The reliability theory of aging and longevity. Journal of Theoretical Biology, 2001, 213(4): 527-545.
Gavrilov, L.A., Gavrilova, N.S. Epidemiology of human longevity: The search for appropriate methodology. Journal of Anti-Aging Medicine, 2001, 4(1): 13-30.
Gavrilov, L.A., Gavrilova, N.S. Biodemographic study of familial determinants of human longevity. Population: An English Selection, 2001, 13(1): 197-222.
Gavrilova, N.S., Gavrilov, L.A. When does human longevity start? Demarcation of the boundaries for human longevity. Journal of Anti-Aging Medicine, 2001, 4(2): 115-124.
Gavrilov, L.A., Gavrilova, N.S. Etude biodemographique des determinants familiaux de la longevite humaine. Population, 2001, 56(1-2): 225-252 (in French).
Gavrilov, L.A., Gavrilova, N.S. Season of birth and human longevity. Journal of Anti-Aging Medicine, 1999, 2(4): 365-366.
Gavrilova, N.S., Gavrilov, L.A. Genetics: Ethnicity. In: David J. Ekerdt (ed.) Macmillan Encyclopedia of Aging, New York, Macmillan Reference USA, 2002, vol.2, 538-539..
Gavrilova, N.S., Gavrilov, L.A. Data resources for biodemographic studies on familial clustering of human longevity. Demographic Research [Online], 1999, vol.1(4): 1-48. Available: http://www.demographic-research.org/Volumes/Vol1/4/
Gavrilov, L.A., Gavrilova, N.S. Is there a reproductive cost for human longevity? J. Anti-Aging Medicine, 1999, 2(2): 121-123.
Carnes, B.A., Olshansky, S.J., Gavrilov, L.A., Gavrilova, N.S., Grahn, D. Human longevity: Nature vs. Nurture - fact or fiction. Perspectives in Biology and Medicine, 1999, 42(3): 422-441.
Gavrilov, L.A., Gavrilova, N.S. How human longevity and species survival could be compatible with high mutation rates. Journal of Anti-Aging Medicine, 1999, 2(2): 153-154.
Gavrilova, N.S., Gavrilov, L.A. et al. Evolution, mutations and human longevity. Human Biology, 1998, 70: 799-804.
Gavrilov, L.A., Gavrilova, N.S. Parental age at conception and offspring longevity. Reviews in Clinical Gerontology, 1997, 7: 5-12.
Gavrilov L.A., Gavrilova, N.S. et al. Mutation load and human longevity. Mutation Research, 1997, 377: 61-62.
Gavrilov, L.A., Gavrilova, N.S. Human reproduction in later life: a research project. Health Care in Later Life, 1997, 2(4): 275-276.
Izsak, J. and Gavrilov, L.A. A typical interdisciplinary topic: questions of the mortality dynamics. Archives of Gerontology and Geriatrics, 1995, 20: 283-293.
Gavrilov, L.A., Gavrilova, N.S. From Leonid A.Gavrilov and Natalia S.Gavrilova. BioEssays, 1994, 16(8): 591-593.
Gavrilov L.A., Gavrilova N.S., Semyonova V.G. Epidemiologic approach to the biology of human life span. Geographia Medica, 1985, 15: 40-64.
Gavrilov, L.A., Gavrilova, N.S., Nosov, V.N. Human life span stopped increasing: why? Gerontology, 1983, 29(3): 176-180.
Gavrilov L.A., Gavrilova N.S. et al. Evolutionary theory, mutations and human life span. Proc. Russian Acad. Sci. [Doklady Akademii Nauk],1998, 359(3): 426-427. English translation published in Doklady Biological Sciences, 1998, 359: 159-160.
Gavrilov
L.A., Gavrilova N.S. et al. Maternal age
and offspring longevity, Proc.
Russian Acad. Sci. [Doklady Akademii Nauk], 1997, 354: 569-572.
English
translation published in Doklady Biological Sciences, 1997,
354:
287-289.
Scientific Communications:
De Grey, Aubrey D. N., Leonid Gavrilov, S. Jay Olshansky, L. Stephen
Coles, Richard G. Cutler, Michael Fossel, and S. Mitchell Harman.
Antiaging technology and pseudoscience.
Letter. Science, 2002,
296: 656-656. Available:
http://www.sciencemag.org/cgi/content/full/296/5568/656a
Gavrilov, L.A., Gavrilova, N.S. The future of long life. Letter. Science, 1998, 281: 1611-1612.
Gavrilov, L.A., Gavrilova, N.S. When Fatherhood Should Stop? Letter. Science, 1997, 277: 17-18.
Gavrilov, L.A., Gavrilova, N.S. Sex and longevity. Letter. Nature, 1994, 367: 520.
Gavrilov, L.A., Gavrilova, N.S. Fruit fly aging and mortality. Letter, Science, 1993, 260(5114): 1565.
Gavrilov, L.A., Gavrilova, N.S. When your time's up. Letter. British
Medical Journal, 1993, 306(6880): 796.
Other Publications:
Gavrilov, L.A., Gavrilova, N.S. Validation of exceptional longevity. Book Review. Population and Development Review, 2000, 26(2): 40-41.
Gavrilov LA, Gavrilova NS et al. Parental age effects on human longevity. Gerontology, 2001,47(Suppl.1): 611.
Gavrilova NS, Gavrilov LA et al. Study of the inheritance of human longevity. Gerontology, 2001, 47(Suppl.1): 611.
Gavrilov, L.A., Gavrilova, N.S., Evdokushkina, G.N., Semyonova, V.G. Familial transmission of human longevity is a function of parental age at reproduction. The Gerontologist, 1999. 39(1): 146.
Gavrilov, L.A., Gavrilova, N.S. et al. Children born to older mothers do not inherit maternal life span. AGE, 1999, 22(3): 27.
Gavrilova, N.S., Gavrilov, L.A., Evdokushkina, G.N., Semyonova, V.G. Demarcation of the boundaries for human longevity. The Gerontologist, 1999. 39(1): 146-147.
Gavrilov, L.A., Gavrilova, N.S., Evdokushkina, G.N., Semyonova, V.G. Human longevity, spontaneous mutations and paternal age. The Gerontologist, 1998, 38(1): 8.
Gavrilova
N.S., Gavrilov L.A., Evdokushkina G.N., Semyonova V.G. Non-linear
transmission
of human longevity from mother to daughter. The Gerontologist,
1998,
38(1): 8.