Brief Statement of Research Interests
Leonid Gavrilov (email@example.com)
My research interests
a broad sense are: (1) to understand the mechanisms of aging and
and (2) to find ways for extension of healthy and productive human
Within this general
in mind, and in collaboration with Dr. Natalia Gavrilova, I reanalyzed
the existing approaches to the aging problem, and came to a number of
research goals described in our book (Gavrilov, Gavrilova, 1991) and
later publications (Gavrilov, Gavrilova, 2001a; b). These
research goals are based on one general idea that deep insights into
nature of aging process could be obtained through innovative methods of
quantitative analysis of lifespan and survival data (available from
genealogical, and demographic studies).
scientific idea, which we would like to elaborate further and to test,
is that early developmental events are important for late-life health
including human longevity. We came to this idea, while developing
a new reliability theory of aging, which states that ‘normal’ organisms
are born with enormous amount of initial damage (Gavrilov, Gavrilova,
Additional support for this idea came from our direct epidemiological
that such early-life conditions as the paternal age at person’s
(Gavrilov, Gavrilova, 2000), the month of person’s birth (Gavrilov,
1999), and the person’s birth order (Gavrilova et al., 2001) proved to
be important predictors of human longevity. We would like to
a large-scale multidisciplinary Research Project on the role of
developmental events and conditions in human aging and longevity
studies on animal models).
More information on
research interests, current work and research experience is available
our website: http://longevity-science.org/
Gavrilov L.A., Gavrilova N.S. (1991). The Biology of Life Span: A Quantitative Approach, NY: Harwood Academic Publisher, 385p.
Gavrilov, L.A., Gavrilova, N.S. (1999). Season of birth and human longevity. Journal of Anti-Aging Medicine, 2(4): 365-366.
Gavrilov, L.A., Gavrilova, N.S. (2000) Human longevity and parental age at conception. In: J.-M.Robine et al. (eds.) Sex and Longevity: Sexuality, Gender, Reproduction, Parenthood, Berlin, Heidelberg: Springer-Verlag, 7-31.
Gavrilov L.A., Gavrilova N.S. (2001a). Epidemiology of human longevity: The search for appropriate methodology. Journal of Anti-Aging Medicine, 4(1): 13-30.
Gavrilov L.A., Gavrilova N.S. (2001b). The reliability theory of aging and longevity. Journal of Theoretical Biology, 213(4): 527-545.
L.A., Evdokushkina G.N., Semyonova, V.G. (2001). Early-life predictors
of human longevity. Paper presented at the 26th annual meeting of
Science History Association, Chicago, November 15-18, 2001.