See new books on the following topics:

Aging -- Alzheimer's -- Anti-Aging -- Aubrey de Grey Ideas -- Biomedical Nanotechnology -- Brain Aging -- Caloric Restriction -- Cancer -- Cardiovascular Health -- Cryonics -- Dementia -- Diabetes -- Estrogen -- Genetics of Aging and Health -- Geriatrics -- Growth Hormone -- Hormones -- Human Longevity -- Immortality -- Life Expectancy -- Life Extension -- Menopause -- Mortality -- Nursing -- Population Aging -- Regenerative Medicine -- Rejuvenation -- Resveratrol -- SENS: Strategies for Engineered Negligible Senescence -- Stem Cell Therapy -- Supplements -- Testosterone -- Vitamins.

Aging, Longevity and Health in the News

Colombia warns on Zika baby risk
Health officials in Colombia are warning that as many as 600 babies could be born with microcephaly this year.

New Hampshire town's surprising warrior against heroin
Eric Adams' phone rings. On the other end is a 36-year-old man, a daily heroin abuser who is finally accepting he's on a "path of destruction" and now desperately wants help.

Vietnam, heroin and the lesson of disrupting any addiction
When the U.S. military launched Operation Golden Flow nearly 45 years ago, no one could have anticipated the impact it would have on the study of addiction, behavior and your brain.

How to keep kids safe on social media
There is still so much we don't know about how a 13-year-old Blacksburg, Virginia, girl got to know an 18-year-old Virginia Tech freshman before he allegedly stabbed her to death.

CTE in the NFL: The tragedy of Fred McNeill
The night before Fred McNeill died in November, he was watching "Monday Night Football." The 63-year-old former Minnesota Viking linebacker and UCLA grad had his gold and blue slippers tucked under his bed. "He loved the game," said his youngest son, Gavin. "He was proud of what he did."

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Brazil Finds Zika Virus in Human Urine and Saliva, but Risk Is Unclear
Scientists warned that the virus might have the potential to spread through kissing and urine, a possibility that clouded the opening of Carnival.

Think Like a Doctor: Drowning on Dry Land
A healthy 67-year-old man develops an annoying little cough that, over the course of a week, worsens and nearly takes his breath away. Can you figure out why?

Well: Think Like a Doctor: Drowning on Dry Land Solved
Readers solve the case of a 67-year-old healthy retiree who suddenly develops knife-like chest pain and a worsening cough.

Health Care Signups Exceed Hopes, With 4 Million Newcomers to Federal Marketp...
About 12.7 million people signed up for health coverage under the Affordable Care Act or had their coverage renewed in the third annual open enrollment season.

How the pros manage Super Bowl jitters
"Pro athletes do experience anxiety, the same way everybody else does," one expert says

What Florida is doing to stop the Zika virus
Florida's hot, humid climate puts its 20 million residents at risk -- along with millions more tourists

Nearly 13 Million Sign Up for Obamacare Health Insurance
About 12.7 million Americans signed up for 2016 health insurance coverage through the government insurance exchanges, surpassing expectations.

CDC Sets Off Firestorm by Warning Women About Alcohol
A well-meaning warning from the federal government about the risks of drinking and pregnancy has set off a firestorm of outrage.

House Panel Accuses Officials of Covering Up Flint Water Crisis
"If it's not criminal, I don't know what is," Marc Edwards, who helped uncover the pollution, told the House Oversight Committee.

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[Editorial] Strength in members
A year ago on this page, I described some of the challenges that science faces in cultivating support from the society it serves. Stepping in as the new Chief Executive Officer of the American Association for the Advancement of Science (AAAS, the publisher of Science), my editorial asked, ?Why science? Why AAAS?? My thoughts about the nature and service of science and the mission and goals of AAAS?the world's largest general science membership organization?have since been focusing on new and rev...

[In Brief] News at a glance
In science news around the world, scientists lose their fight to study 9000-year-old bones in California, a twisty stellarator begins its scientific work in earnest, a U.K. scientist gets permission to modify human embryos, more than 300 Nobel laureates sign a letter calling on Iran to free a jailed chemist, the United States pledges $1 billion to jump-start its "moonshot" to cure cancer, and more. Also, disgraced stem cell researcher Haruko Obokata tells her side of the story of the unraveling ...

[In Depth] Risky reactor fuel to linger
Since 1978, the United States and other nations have been pushing to eliminate highly enriched uranium (HEU)?which a terrorist or rogue nation could use to make a bomb?as fuel in civilian research reactors. But achieving that goal will take far longer than previously hoped, according to a study from the National Academies of Sciences, Engineering, and Medicine. Instead of 2018, a timeframe of 2035 is more realistic, the 28 January report concludes. Dozens of civilian research reactors have close...

[In Depth] Calling all failed replication experiments
A growing number of retracted papers have stirred concerns about irreproducible results in biomedical research. Now, the biotech company Amgen and prominent biochemist Bruce Alberts have created a new online journal that aims to lift the curtain on often-hidden data: failed efforts to confirm other groups' published papers. Amgen is seeding the publication with reports on its own futile attempts to replicate three studies in obesity and neurodegenerative disease and hopes other companies will fo...

[Feature] What makes DARPA tick?
Founded in 1958 in the aftermath of Sputnik, the Defense Advanced Research Projects Agency (DARPA) is supposed to make sure the U.S. military holds a technological edge over its enemies. Over the decades since, it has earned a reputation for using out-of-the-box thinking to solve what defense officials like to call "DARPA-hard" problems. The key to its success, say dozens of people who have worked for or with DARPA, is its cadre of program managers. Some call them DARPA's "secret sauce." Althoug...

[Feature] Biology came late, and arrived with a bang
After the Cold War ended, U.S. military leaders began to worry that rogue states might wage bioterrorism attacks on both U.S. soldiers and civilian populations. That new threat exposed a significant hole in the Defense Advanced Research Projects Agency's (DARPA's) portfolio: the life sciences. Remarkably, the agency didn't hire its first biologist until 1990. But over the next quarter-century it made up for lost time, and in June 2014 DARPA put the life sciences on an equal footing with other di...

[Perspective] The mite that jumped, the bee that traveled, the disease that f...
European honeybees are among the best-studied and most widely recognized insect species in the world. Originally kept for honey production, they have become the flagship species for pollination and large-scale agriculture. Since large colony losses were reported across the United States in 2006, researchers have investigated the myriad factors that contribute to the decline in honeybee populations. In particular, the aptly named Varroa destructor mite (see the photo) and the deformed wing virus ...

[Perspective] Throttling back the heart's molecular motor
A young athlete collapses and dies during competition. Autopsy reveals an enlarged heart with thickened walls in which the cardiac muscle cells are in disarray and surrounded by fibrotic tissue. Until 1990, the cause of such sudden death was unknown. This devastating condition, called familial hypertrophic cardiomyopathy (HCM), was eventually linked to a mutation in myosin (1), the heart's molecular motor. Today, more than 300 separate HCM-causing mutations have been identified throughout the my...

[Perspective] Addressing an antiferromagnetic memory
Spintronics (1) is one of the most commercially successful nanotechnologies. The invention of the giant-magnetoresistance spin valve (2) revolutionized the magnetic recording industry, enabling the immensely cheap, high-density disk drive storage on which the data centers that support our insatiable demand for cloud computing, social networking, and video sharing technologies rely. The combination of magnetic tunneling junctions (3) and spin-transfer torque (STT) (4) has brought about the prospe...

[Perspective] Aging, alopecia, and stem cells
Many tissues turn over during adult life, and declines in this process are associated with the progression of aging. Whether renewal is continual (as in the intestinal villi) or episodic (as in hair follicles), it is mainly attributed to somatic stem cells. One fundamental question is whether a decline of tissue renewal reflects the lifelong accumulation of external insults or the internal progression of a clock within stem cells? On pages 613 and 575 of this issue, Wang et al. (1) and Matsumura...

[Perspective] Nanoparticles meet their sticky ends
The first studies showing that DNA could be grafted onto the surfaces of metal nanoparticles (NPs) (1, 2) provided a glimpse into the potential of using genetic material to program NP assembly. With major advances in DNA nanotechnology (3, 4) in the subsequent years, researchers have just begun to harness the molecular and nanoscale precision that DNA offers in the construction of ordered three-dimensional (3D) NP superlattices. In this issue, two studies show how hierarchically structured DNA i...

[Policy Forum] Taking race out of human genetics
In the wake of the sequencing of the human genome in the early 2000s, genome pioneers and social scientists alike called for an end to the use of race as a variable in genetic research (1, 2). Unfortunately, by some measures, the use of race as a biological category has increased in the postgenomic age (3). Although inconsistent definition and use has been a chief problem with the race concept, it has historically been used as a taxonomic categorization based on common hereditary traits (such as...

[Book Review] Losing our taste for diversity
Our modern food system is not driven by taste but instead by factors like consistency, predictability, low cost, and high yield. In Bread Wine Chocolate, Simran Sethi explores how the same features that enabled the worldwide distribution of once-exotic foods like coffee and chocolate have now so drastically altered how those products are made that we risk losing them altogether. Author: Christopher Kemp

[Book Review] Public enemy
Four years after his death, one of the most important figures of the Chinese scientific establishment has given us a first-person account of growing to manhood and eminence in revolutionary China. The Most Wanted Man in China is both a memoir and a personal testament of Fang Lizhi?a renowned scientist, humane scholar, political activist, intractable enemy of authoritarian government, and courageous advocate of human rights. Author: Irving A. Lerch

[Letter] Psychosocial factors key to healthy aging
Author: Theodore D. Cosco

[This Week in Science] Quiescent and aging hair follicle stem cells
Author: Beverly A. Purnell

[Review] Why do batteries fail?
Battery failure and gradual performance degradation (aging) are the result of complex interrelated phenomena that depend on battery chemistry, design, environment, and the actual operation conditions. The current available knowledge on these matters results from a vast combination of experimental and modeling approaches. We explore the state of the art with respect to materials as well as usage (temperature, charge/discharge rate, etc.) for lead-acid, nickel-cadmium, nickel?metal hydride, and li...

[Research Article] Hair follicle aging is driven by transepidermal eliminatio...
Hair thinning and loss are prominent aging phenotypes but have an unknown mechanism. We show that hair follicle stem cell (HFSC) aging causes the stepwise miniaturization of hair follicles and eventual hair loss in wild-type mice and in humans. In vivo fate analysis of HFSCs revealed that the DNA damage response in HFSCs causes proteolysis of type XVII collagen (COL17A1/BP180), a critical molecule for HFSC maintenance, to trigger HFSC aging, characterized by the loss of stemness signatures and b...

[Report] Diamond family of nanoparticle superlattices
Diamond lattices formed by atomic or colloidal elements exhibit remarkable functional properties. However, building such structures via self-assembly has proven to be challenging because of the low packing fraction, sensitivity to bond orientation, and local heterogeneity. We report a strategy for creating a diamond superlattice of nano-objects via self-assembly and demonstrate its experimental realization by assembling two variant diamond lattices, one with and one without atomic analogs. Our a...

[Report] Electrical switching of an antiferromagnet
Antiferromagnets are hard to control by external magnetic fields because of the alternating directions of magnetic moments on individual atoms and the resulting zero net magnetization. However, relativistic quantum mechanics allows for generating current-induced internal fields whose sign alternates with the periodicity of the antiferromagnetic lattice. Using these fields, which couple strongly to the antiferromagnetic order, we demonstrate room-temperature electrical switching between stable co...

[Report] Holocene deceleration of the Greenland Ice Sheet
Recent peripheral thinning of the Greenland Ice Sheet is partly offset by interior thickening and is overprinted on its poorly constrained Holocene evolution. On the basis of the ice sheet?s radiostratigraphy, ice flow in its interior is slower now than the average speed over the past nine millennia. Generally higher Holocene accumulation rates relative to modern estimates can only partially explain this millennial-scale deceleration. The ice sheet?s dynamic response to the decreasing proportion...

[Report] Foxc1 reinforces quiescence in self-renewing hair follicle stem cells
Stem cell quiescence preserves the cell reservoir by minimizing cell division over extended periods of time. Self-renewal of quiescent stem cells (SCs) requires the reentry into the cell cycle. In this study, we show that murine hair follicle SCs induce the Foxc1 transcription factor when activated. Deleting Foxc1 in activated, but not quiescent, SCs causes failure of the cells to reestablish quiescence and allows premature activation. Deleting Foxc1 in the SC niche of gene-targeted mice leads t...

Experts: Screen More Kids for Middle Ear Fluid
Children with developmental issues, syndromes, or conditions that put them at high risk for fluid in the middle ear should be checked for it, according to new expert guidelines. WebMD has the details.

Allergies, Asthma Tied to Lower Brain Cancer Risk
Researchers found 30 percent lower odds for those with respiratory allergies and eczema

Food Allergy Myths and Facts
WebMD separates fact and fiction about food allergies, including the difference between an allergy and a sensitivity, whether children outgrow allergies, and more.

NFL Linemen Keep Growing, Putting Health at Risk
Some players are topping out at 400 pounds -- and more

Depression May Boost Seniors' Risk for These
Doctors should monitor older adults for low mood, researchers say

How to Take Care of Your Joints
WebMD explains how exercise and weight loss can help keep your osteoarthritis from getting worse.

ADHD May Be Tied to Obesity Risk for Girls
Impulsiveness, eating disorders may help explain possible link, researcher says

Steroids May Help More Than Just Premature Babies
Researchers found they reduced risk for respiratory problems in infants born at 34 to 36 weeks

Insurers Accelerate Moves To Limit Health-Law Enrollment
Major changes in broker compensation are designed to discourage enrollment of the sickest, say consumer advocates.

Head Injuries Tied to Buildup of Alzheimer's Plaques, Small Study Finds
But it's too soon to suggest that people should avoid contact sports, researcher says

4 Myths About Miscarriages
WebMD covers common myths about miscarriages and what you really need to know about them.

Expert Answers for Diaper Rash Questions
Do most of your questions about diaper rash come up after hours, when you're holding a crying baby? Help is on the way. Here, pediatricians offer their best advice to help ease your little one?s discomfort.

Red Cross Moves to Keep Zika Out of Blood Supply
Agency asks potential donors who have traveled to areas where virus is active to wait 28 days

Anxiety Meds Won't Raise Seniors' Dementia Risk
Research may ease some concerns about use of benzodiazapines, but side effects do exist

When Seniors Stop Driving, Worse Health May Result
Depression and mental, physical declines stood out in research review

Where infants sleep may affect how long they are breastfed
A new study indicates that mothers who frequently sleep, or bed-share, with their infants consistently breastfeed for longer than mothers who do not bed-share. Also, pregnant women who expressed a strong motivation to breastfeed were more likely to bed-share frequently once their baby was born. The findings, which come from a study of 678 women in a randomized breastfeeding trial who were recruited at mid-pregnancy, question whether recommendations to avoid bed-sharing due to concerns such as su...

Record Missouri flooding was humanmade calamity, scientist says
Why was the New Year's flood in Missouri so bad? Most news reports blamed it on the heavy rain, but a professor of earth and planetary sciences says analysis of the flood data shows much of the damage was due to recent modifications to the river.

Study evaluates pay-for-performance program for Medicaid children in an ACO
The first pay-for-performance (P4P) evaluation of pediatricians under a full-risk Medicaid accountable care organization (ACO) for children shows P4P incentives were partially responsible for higher performance on quality measures across Partners for Kids' primary care network of employed and affiliated physicians.

Prehistoric mystery meat put to the test (spoiler alert: It?s not woolly mamm...
Sorry, Explorers Club, but woolly mammoth is no longer on the menu. Neither is the giant ground sloth.

Chromosomes reconfigure as cell division ends
Cells reach a state called senescence when they stop dividing in response to DNA damage. This change can matter greatly to health, but scientists do not yet have a clear picture of how this change impacts the genome. A new study shows that a cell's chromosomes become physically reconfigured at senescence, leading to significant differences in what genes are expressed.

'Pushback' against constant connectivity also reflected in images
People expressing the wish to resist constant online connectivity -- dubbed "pushback" by researchers -- is manifested as powerfully in images as in text, further study has found.

Cells that show where things are going
The ability to see the direction in which something is moving is vital for survival. Only in this way is it possible to avoid predators, capture prey or, as humans in a modern world, cross a road safely. However, the direction of motion is not explicitly represented at the level of the photoreceptors but rather must be calculated by subsequent layers of nerve cells. Scientists have now discovered that, in fruit flies, four classes of nerve cell are involved in calculating directionally selective...

Central Appalachia flatter due to mountaintop mining
Forty years of mountaintop coal mining have made parts of Central Appalachia 60 percent flatter than they were before excavation, researchers say. This study, which compares pre- and post-mining topographic data in southern West Virginia, is the first to examine the large-scale impact of mountaintop mining on landscape topography and how the changes influence water quality.

Smart thermostat puts energy money saving at household fingertips
Researchers are aiming to develop a 'smart' thermostat to help UK households save money on their energy bills. The prototype autonomous device allows users to control their heating based on the price they want to pay rather than setting it by temperature alone, which existing smart thermostats such as Nest, do.

Parental preference for boys damages girls? self-esteem and happiness
While most studies of parental sex discrimination explore the devastating social and demographic effects of a cultural preference for boys, a new study examines its psychological effects on the girls themselves. 

Super-resolution microscope allows visualization of the mechanism that mainta...
Cells are not uniform spheres; they generally come in a variety of disparate shapes. In the broadest sense, this variation in shapes is known as cell polarity, and it is an essential property for a variety of cell functions. Growth in accordance with their polarity allows cells to shape themselves in forms appropriate to their function. It has been found that the establishment and maintenance of polarity is governed by the interdependent relationship between the polarity marker protein on the pl...

Prunetin prolongs lifespan in male fruit flies and enhances overall health
Here's a reason for men to eat their lima beans -- if research in male fruit flies holds up, it might help you live longer. A new research report shows that administering an oral dose of prunetin to male fruit flies extends lifespan, increases fitness levels, and improves their glucose balance.

Scientists discover molecular link between psychiatric disorders and type 2 d...
Scientists show that a gene called 'DISC1,' which is believed to play a role in mental health disorders, such as schizophrenia, bipolar disorder and some forms of depression, influences the function of pancreatic beta cells which produce insulin to maintain normal blood glucose levels.

Researchers identify striking genomic signature shared by five types of cancer
Researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer. The specific signature results from a chemical modification of DNA called methylation, which can control the expression of genes like a dimmer on a light switch. Based on this advance, the researchers hope to spur development of a blood test that can be used to diagnose a variety of cancers at early stages.

Motorboat noise gives predators a deadly advantage
Biologists found that noise from passing motorboats increases stress levels in young coral reef fish and reduces their ability to flee from predators. As a consequence they are captured more easily and their survival chances are halved.

First-of-its-kind study explains why rest is critical after a concussion
Neuroscientists say rest -- for more than a day -- is critical for allowing the brain to reset neural networks and repair any short-term injury. This new study in mice also shows that repeated mild concussions with only a day to recover between injuries leads to mounting damage and brain inflammation that remains evident a year after injury.

A cancer's surprise origins caught in action
Researchers have, for the first time, visualized the origins of cancer from the first affected cell and watched its spread in a live animal. Their work could change the way scientists understand melanoma and other cancers and could lead to new, early treatments before the cancer has taken hold.

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As Flint Fought to Be Heard, Virginia Tech Team Sounded Alarm
Young scientists and their professor helped force Michigan officials to acknowledge the elevated levels of lead in drinking water, and now the government has requested the team?s assistance.

Wood Shop Enters the Age of High-Tech
The D.I.Y. movement ? to get students creating, be it for fun, for art or for entrepreneurship ? is booming. There?s even a MOOC on how to teach tinkering.

Brazil Finds Zika Virus in Human Urine and Saliva, but Risk Is Unclear
Scientists warned that the virus might have the potential to spread through kissing and urine, a possibility that clouded the opening of Carnival.

Trilobites: In a Slovenian Cave, Hoping for a Batch of Baby ?Dragons?
To see the olms in Postojna Cave, you?ll need to take an underground train. But you might be rewarded with a glimpse of their crystal clear eggs.

Blackboard: Create Your Own Language, for Credit
HBO?s ?Game of Thrones? turns constructed language into a hit.

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